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The antibody against ZFPM1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ZFPM1 (NP_722520.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against ZFPM1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ZFPM1 (NP_722520.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-07215A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFPM1 |
| Target Synonyms | FOG; FOG1; ZNF408; ZNF89A; ZC2HC11A; ZFPM1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HEL, K-562, Mouse spleen | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ZFPM1 (NP_722520.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8IX07 | Immunogen Sequence |
Uniprot Id
Q8IX07
Target Species
Human
Target Name
ZFPM1
Target Full Name
Zinc finger protein ZFPM1
Target Function
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2
Target Subcellular Location
Nucleus.
Target Protein Families
FOG (Friend of GATA) family
Target Tissue Specificity
Mainly expressed in hematopoietic tissues. Also expressed in adult cerebellum, stomach, lymph node, liver and pancreas. Expressed in fetal heart, liver and spleen.
Target Synonyms
FOG-1; FOG1_HUMAN; Friend of GATA 1; Friend of GATA protein 1; Friend of GATA1; ZFPM1; Zinc finger protein; Zinc finger protein 89A; Zinc finger protein multitype 1; Zinc finger protein ZFPM1
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