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The antibody against ZFX was raised in rabbit using the Recombinant Human Zinc finger X-chromosomal protein (711-805AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ZFX was raised in rabbit using the Recombinant Human Zinc finger X-chromosomal protein (711-805AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-05806A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFX |
| Target Synonyms | X-linked antibody; Zinc Finger X Chromosomal Protein antibody; Zinc finger X-chromosomal protein antibody; ZNF926 antibody, X-linked zinc finger protein antibody; zfx antibody; ZFX_HUMAN antibody; Zinc finger protein | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger X-chromosomal protein (711-805AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P17010 |
Uniprot Id
P17010
Target Species
Human
Target Name
ZFX
Target Full Name
Zinc finger X-chromosomal protein
Target Function
Probable transcriptional activator.
Target Subcellular Location
Nucleus.
Target Protein Families
Krueppel C2H2-type zinc-finger protein family, ZFX/ZFY subfamily
Target Synonyms
X-linked zinc finger protein; zfx; ZFX_HUMAN; Zinc finger protein, X-linked; Zinc Finger X Chromosomal Protein; Zinc finger X-chromosomal protein; ZNF926
Target Background
This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.
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