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The antibody against ZFYVE1 was raised in rabbit using the Recombinant Human Zinc finger FYVE domain-containing protein 1 protein (544-762aa) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ZFYVE1 was raised in rabbit using the Recombinant Human Zinc finger FYVE domain-containing protein 1 protein (544-762aa) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-54869A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFYVE1 |
| Target Synonyms | DFCP1 KIAA1589 TAFF1 ZNFN2A1, ZFYVE1, Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1) | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger FYVE domain-containing protein 1 protein (544-762aa) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HBF4 |
Uniprot Id
Q9HBF4
Target Species
Human
Target Name
ZFYVE1
Target Full Name
Zinc finger FYVE domain-containing protein 1
Target Function
Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis. Regulates the morphology, size and distribution of LDs. Mediates the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts by forming a complex with RAB18 and ZW10. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through FYVE-type zinc finger.
Target Subcellular Location
Golgi apparatus, Golgi stack. Golgi apparatus. Endoplasmic reticulum. Lipid droplet. Preautophagosomal structure. Mitochondrion.
Target Tissue Specificity
[Isoform 2]: Highly expressed in heart. Also detected in the testis.; [Isoform 1]: Expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Highly expressed in heart.
Target Synonyms
ZFYVE1; DFCP1; KIAA1589; TAFF1; ZNFN2A1; PP10436Zinc finger FYVE domain-containing protein 1; Double FYVE-containing protein 1; SR3; Tandem FYVE fingers-1
Target Background
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants.
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