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The antibody against ZMYM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against ZMYM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-03362A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZMYM3 |
| Target Synonyms | MYM; XFIM; ZNF261; DXS6673E; ZNF198L2; ZMYM3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | LLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSVSQRA | Uniprot ID | Q14202 |
Uniprot Id
Q14202
Target Species
Human
Target Name
ZMYM3
Target Full Name
Zinc finger MYM-type protein 3
Target Function
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Target Involvement
A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.
Target Synonyms
DXS6673E; KIAA0385; MYM; XFIM; ZFP261; Zinc finger MYM type 3; Zinc finger MYM type protein 3; Zinc finger MYM-type protein 3; Zinc finger protein 261; ZMYM 3; Zmym3; ZMYM3_HUMAN; ZNF 261; ZNF198L2; ZNF261
Target Background
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
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