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The antibody against ZNF274 was raised in rabbit using the Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ZNF274 was raised in rabbit using the Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-18680A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZNF274 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96GC6 |
Uniprot Id
Q96GC6
Target Species
Human
Target Name
ZNF274
Target Full Name
Neurotrophin receptor-interacting factor homolog
Target Function
Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions.
Target Subcellular Location
Cytoplasm. Nucleus, nucleolus.
Target Protein Families
Krueppel C2H2-type zinc-finger protein family
Target Synonyms
ZNF274; ZKSCAN19; SP2114Neurotrophin receptor-interacting factor homolog; Zinc finger protein 274; Zinc finger protein HFB101; Zinc finger protein with KRAB and SCAN domains 19; Zinc finger protein zfp2; Zf2
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