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The antibody against ZNF408 was raised in rabbit using the Recombinant Human Zinc finger protein 408 protein (317-635AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ZNF408 was raised in rabbit using the Recombinant Human Zinc finger protein 408 protein (317-635AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using ZNF408 Antibody at dilution of 1:100
| Cat.No | ADC-15588A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZNF408 |
| Target Synonyms | EVR6 antibody; PFM14 antibody; PR domain zinc finger protein 17 antibody; PRDM17 antibody; RP72 antibody; Zinc finger protein 408 antibody; ZN408_HUMAN antibody; ZNF408 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger protein 408 protein (317-635AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H9D4 |
Uniprot Id
Q9H9D4
Target Species
Human
Target Name
ZNF408
Target Full Name
Zinc finger protein 408
Target Function
May be involved in transcriptional regulation.
Target Involvement
Vitreoretinopathy, exudative 6 (EVR6); Retinitis pigmentosa 72 (RP72)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highest expression is observed in adult retina; abundantly expressed in the fetal eye. In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at
Target Synonyms
EVR6; PFM14; PR domain zinc finger protein 17; PRDM17; RP72; Zinc finger protein 408; ZN408_HUMAN; ZNF408
Target Background
The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP).
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