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The antibody against ZNF645 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase CBLL2 protein (200-413AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against ZNF645 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase CBLL2 protein (200-413AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-09962A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZNF645 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human E3 ubiquitin-protein ligase CBLL2 protein (200-413AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N7E2 |
Uniprot Id
Q8N7E2
Target Species
Human
Target Name
CBLL2
Target Full Name
E3 ubiquitin-protein ligase CBLL2
Target Function
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Exclusively expressed in testis and sperm, including spermatocytes, round and elongated spermatids, and Leydig cells.
Target Synonyms
CBLL2; ZNF645E3 ubiquitin-protein ligase CBLL2; EC 2.3.2.27; Cbl proto-oncogene-like protein 2; RING-type E3 ubiquitin transferase ZNF645; Zinc finger protein 645; c-Cbl-like protein 2
Target Background
This gene encodes a member of the zinc finger domain-containing protein family. This family member contains both a RING-type and a C2H2-type of zinc finger domain, and it may function as an E3 ubiquitin-protein ligase. Protein localization suggests a role in human sperm production and quality control.
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