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The antibody against PA was raised in rabbit using the Recombinant Influenza A virus Polymerase acidic protein (1-716AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PA was raised in rabbit using the Recombinant Influenza A virus Polymerase acidic protein (1-716AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-43946A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PA |
| Target Synonyms | PAPolymerase acidic protein antibody; EC 3.1.-.- antibody; RNA-directed RNA polymerase subunit P2 antibody | Form | Liquid |
| Species Reactivity | Influenza A virus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Influenza A virus Polymerase acidic protein (1-716AA) | Target Species | Influenza A virus (strain A/USA:Huston/AA/1945 H1N1) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A4U6V9 |
Uniprot Id
A4U6V9
Target Species
Influenza A virus
Target Name
PA
Target Function
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
Target Subcellular Location
Host cytoplasm. Host nucleus.
Target Protein Families
Influenza viruses PA family
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