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The antibody against Fcmr was raised in rabbit using the Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against Fcmr was raised in rabbit using the Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-45638A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FCMR |
| Target Synonyms | Fcmr antibody; Faim3 antibody; TosoFas apoptotic inhibitory molecule 3 antibody; IgM Fc fragment receptor antibody; Regulator of Fas-induced apoptosis Toso antibody | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A1KXC4 |
Uniprot Id
A1KXC4
Target Species
Mouse
Target Name
FCMR
Target Full Name
Immunoglobulin mu Fc receptor
Target Function
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Target Subcellular Location
Membrane; Single-pass membrane protein.
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