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The antibody against Gp2 was raised in rabbit using the Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 protein (22-531AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Gp2 was raised in rabbit using the Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 protein (22-531AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-18069A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Gp2 |
| Target Synonyms | Gp2 antibody; Pancreatic secretory granule membrane major glycoprotein GP2 antibody; Pancreatic zymogen granule membrane protein GP-2 antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 protein (22-531AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9D733 |
Uniprot Id
Q9D733
Target Species
Mouse
Target Name
GP2
Target Full Name
Pancreatic secretory granule membrane major glycoprotein GP2
Target Function
Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participate in the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.
Target Subcellular Location
Zymogen granule membrane; Lipid-anchor, GPI-anchor. Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-anchor. Endosome.
Target Tissue Specificity
Specifically expressed by M (microfold) cells which are atypical epithelial cells of the intestine.
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