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The antibody against Ltbp1 was raised in rabbit using the Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Ltbp1 was raised in rabbit using the Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-11803A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Ltbp1 |
| Target Synonyms | Ltbp1Latent-transforming growth factor beta-binding protein 1 antibody; LTBP-1 antibody; Transforming growth factor beta-1-binding protein 1 antibody; TGF-beta1-BP-1 antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8CG19 |
Uniprot Id
Q8CG19
Target Species
Mouse
Target Name
LTBP1
Target Full Name
Latent-transforming growth factor beta-binding protein 1
Target Function
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.
Target Subcellular Location
Secreted. Secreted, extracellular space, extracellular matrix.
Target Protein Families
LTBP family
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