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The antibody against Lypla1 was raised in rabbit using the Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Lypla1 was raised in rabbit using the Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-46147A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Lypla1 |
| Form | Liquid | Species Reactivity | Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P97823 |
Uniprot Id
P97823
Target Species
Mouse
Target Name
LYPLA1
Target Full Name
Acyl-protein thioesterase 1
Target Function
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Could also depalmitoylate ADRB2. Acts as a lysophospholipase hydrolyzing various lysophospholipids including lysophosphatidylcholine (lyso-PC), lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS)(PubMed:9139730). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.
Target Subcellular Location
Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum.
Target Protein Families
AB hydrolase superfamily, AB hydrolase 2 family
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