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The antibody against Map3k1 was raised in rabbit using the Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against Map3k1 was raised in rabbit using the Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
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| Cat.No | ADC-46452A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAP3K1 |
| Form | Liquid | Species Reactivity | Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53349 |
Uniprot Id
P53349
Target Species
Mouse
Target Name
MAP3K1
Target Full Name
Mitogen-activated protein kinase kinase kinase 1
Target Function
Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Target Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
Target Tissue Specificity
Highly expressed in the heart and spleen while a lower level expression is seen in the liver.
Target Research Area
Others
Target Synonyms
Map3k1; Mekk; Mekk1; Mitogen-activated protein kinase kinase kinase 1; EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1
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