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The antibody against Prf1 was raised in rabbit using the Recombinant Mouse Perforin-1 protein (21-554AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Prf1 was raised in rabbit using the Recombinant Mouse Perforin-1 protein (21-554AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-21622A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Prf1 |
| Target Synonyms | Prf1 antibody; Pfp antibody; Perforin-1 antibody; P1 antibody; Cytolysin antibody; Lymphocyte pore-forming protein antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Perforin-1 protein (21-554AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10820 |
Uniprot Id
P10820
Target Species
Mouse
Target Name
PRF1
Target Full Name
Perforin-1
Target Function
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Target Subcellular Location
Cytolytic granule. Secreted. Cell membrane; Multi-pass membrane protein. Endosome lumen.
Target Protein Families
Complement C6/C7/C8/C9 family
Target Tissue Specificity
Detected in cytotoxic T-lymphocytes and natural killer cells.
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