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The antibody against PMI was raised in rabbit using the Recombinant Plasmodium falciparum PMI protein (125-452aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against PMI was raised in rabbit using the Recombinant Plasmodium falciparum PMI protein (125-452aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: recombinant protein | All lanes: PMI Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 39 kDa | Observed band size: 39 kDa
| Cat.No | ADC-54721A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PMI |
| Target Synonyms | Plasmepsin-1 (EC 3.4.23.38) (Aspartic hemoglobinase I) (PfAPG) | Form | Liquid |
| Species Reactivity | Plasmodium falciparum | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Immunogen Description | Recombinant Plasmodium falciparum PMI protein (125-452aa) | Target Species | Plasmodium falciparum |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P39898 |
Uniprot Id
P39898
Target Species
Plasmodium falciparum
Target Name
PMI
Target Function
During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).
Target Subcellular Location
Membrane; Single-pass type II membrane protein. Vacuole lumen. Vacuole membrane.
Target Protein Families
Peptidase A1 family
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