Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The recombinant antibody against PTH1R was produced using a synthesized peptide derived from human Parathyroid Hormone Receptor 1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The recombinant antibody against PTH1R was produced using a synthesized peptide derived from human Parathyroid Hormone Receptor 1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
$350.00
Western Blot | Positive WB detected in: U-251 whole cell lysate, THP-1 whole cell lysate, Ntera-2 whole cell lysate | All lanes: PTH1R antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 67 kDa | Observed band size: 72, 55 kDa
| Cat.No | ADC-56855A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | PTH1R | Target Synonyms | Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor), PTH1R, PTHR PTHR1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human Parathyroid Hormone Receptor 1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03431 |
Uniprot Id
Q03431
Target Species
Human
Target Name
PTH1R
Target Full Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
Target Function
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Target Involvement
Jansen metaphyseal chondrodysplasia (JMC); Chondrodysplasia Blomstrand type (BOCD); Enchondromatosis multiple (ENCHOM); Eiken skeletal dysplasia (EISD); Primary failure of tooth eruption (PFE)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Tissue Specificity
Expressed in most tissues. Most abundant in kidney, bone and liver.
Target Synonyms
PFE; EKNS; PTHR; PTHR1; PTH1R
Target Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
