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Rabbit Dop1R1 Polyclonal Antibody

The antibody against Dop1R1 was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) Dop1R1 protein (20-142aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.

ADC-55400A

The antibody against Dop1R1 was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) Dop1R1 protein (20-142aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-55400A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDop1R1
Target SynonymsDopamine receptor 1 (D-DOP1) (DmDop1) (dDA1) (Dopamine 1-like receptor 1) Dop1R1 DopR DopR1 DopR35EF CG9652FormLiquid
Species ReactivityDrosophila melanogaster (Fruit fly)IsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification MethodProtein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Drosophila melanogaster (Fruit fly) Dop1R1 protein (20-142aa )Target SpeciesDrosophila melanogaster (Fruit fly)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP41596
Background Information
  • Uniprot Id

    P41596

  • Target Species

    Drosophila melanogaster

  • Target Name

    DOP1R1

  • Target Function

    Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Might be involved in the processing of visual information and/or visual learning. Important for Pavlovian conditioning: required in the mushroom body as a receptor conveying unconditional stimuli information, has a role in memory formation for aversive and appetitive learning. Sleep-deprivation-induced impairments in learning can be partially explained through alterations in dopamine signaling, Dop1R1 expression levels are reduced; sleep may have a role in restoring dopamine homeostasis.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed in the larval and adult CNS in structures that mediate higher-order brain functions such as learning, memory and motor control: in the mushroom body neuropil and four unpaired neurons in each thoracic segment. The adult CNS has intense expressio

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