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Rabbit Intermediate capsid protein VP6 Polyclonal Antibody, Biotin conjugated

The antibody against Intermediate capsid protein VP6 was raised in rabbit using the Recombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-49860A

The antibody against Intermediate capsid protein VP6 was raised in rabbit using the Recombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-49860A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIntermediate capsid protein VP6
Target SynonymsIntermediate capsid protein VP6 antibodyFormLiquid
Species ReactivityRotavirus AIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateBiotin conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA)Target SpeciesRotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) (RV-A)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP04509
Background Information
  • Uniprot Id

    P04509

  • Target Species

    Rotavirus A

  • Target Function

    Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.

  • Target Subcellular Location

    Virion.

  • Target Protein Families

    Rotavirus VP6 family

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