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The antibody against otop1 was raised in rabbit using the Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) otop1 protein (406-518aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The antibody against otop1 was raised in rabbit using the Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) otop1 protein (406-518aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: recombinant protein | All lanes: otop1 Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 31 kDa | Observed band size: 31 kDa
| Cat.No | ADC-55290A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OTOP1 |
| Target Synonyms | Otopetrin-1 otop1 | Form | Liquid |
| Species Reactivity | Danio rerio (Zebrafish) (Brachydanio rerio) | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) otop1 protein (406-518aa) | Target Species | Danio rerio (Zebrafish) (Brachydanio rerio) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7ZWK8 |
Uniprot Id
Q7ZWK8
Target Species
Zebrafish
Target Name
OTOP1
Target Function
Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Otopetrin family
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