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The antibody against Phospholipase D LamSicTox-alphaIC1 was raised in rabbit using the Recombinant Loxosceles amazonica Phospholipase D LamSicTox-alphaIC1 protein (1-273AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Phospholipase D LamSicTox-alphaIC1 was raised in rabbit using the Recombinant Loxosceles amazonica Phospholipase D LamSicTox-alphaIC1 protein (1-273AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-45432A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Phospholipase D LamSicTox-alphaIC1 |
| Form | Liquid | Species Reactivity | Loxosceles amazonica |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Loxosceles amazonica Phospholipase D LamSicTox-alphaIC1 protein (1-273AA) | Target Species | Loxosceles amazonica (Recluse spider) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | C0JAZ9 |
Uniprot Id
C0JAZ9
Target Species
Loxosceles amazonica
Target Function
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate. This toxin acts on sphingomyelin (SM). It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG). It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products. Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation.
Target Subcellular Location
Secreted.
Target Protein Families
Arthropod phospholipase D family, Class II subfamily
Target Tissue Specificity
Expressed by the venom gland.
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