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Rabbit anti-Rabies virus G Polyclonal Antibody, FITC conjugated

The antibody against G was raised in rabbit using the Recombinant Rabies virus Glycoprotein protein (20-459AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-46110A

The antibody against G was raised in rabbit using the Recombinant Rabies virus Glycoprotein protein (20-459AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-46110A ClonalityPolyclonal
Host SpeciesRabbitTarget NameG
Target SynonymsGGlycoprotein antibodyFormLiquid
Species ReactivityRabies virusIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateFITC conjugatedStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Rabies virus Glycoprotein protein (20-459AA)Target SpeciesRabies virus
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP03524
Background Information
  • Uniprot Id

    P03524

  • Target Species

    Rabies virus

  • Target Name

    G

  • Target Function

    Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

  • Target Subcellular Location

    Virion membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Lyssavirus glycoprotein family

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