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Rabbit anti-Rabies virus P Polyclonal Antibody

The antibody against P was raised in rabbit using the Recombinant Rabies virus Phosphoprotein protein (1-297AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-50135A

The antibody against P was raised in rabbit using the Recombinant Rabies virus Phosphoprotein protein (1-297AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-50135A ClonalityPolyclonal
Host SpeciesRabbitTarget NameP
Target SynonymsP antibody; Phosphoprotein antibody; Protein P antibody; Protein M1 antibodyFormLiquid
Species ReactivityRabies virusIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Rabies virus Phosphoprotein protein (1-297AA)Target SpeciesRabies virus
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP69480
Background Information
  • Uniprot Id

    P69480

  • Target Species

    Rabies virus

  • Target Name

    P

  • Target Function

    Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body.

  • Target Subcellular Location

    [Phosphoprotein]: Virion. Host cytoplasm.; [Isoform P2]: Host cytoplasm.; [Isoform P3]: Host nucleus.; [Isoform P4]: Host nucleus.; [Isoform P5]: Host nucleus.

  • Target Protein Families

    Lyssavirus protein P family

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