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| Cat.No | ACP12343 | Target Name | ADI1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-179 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BV57 |
|---|
Uniprot Id
Q9BV57
Target Species
Human
Target Name
ADI1
Target Full Name
Acireductone dioxygenase
Target Function
Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
Target Subcellular Location
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14.
Target Protein Families
Acireductone dioxygenase (ARD) family
Target Tissue Specificity
Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.
Target Synonyms
1 2 dihydroxy 3 keto 5 methylthiopentene dioxygenase; 1; 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Aci reductone dioxygenase; Acireductone dioxygenase (Fe(2+) requiring); Acireductone dioxygenase (Ni(2+) requiring); Acireductone dioxygenase (Ni(2+)-requiring); Acireductone dioxygenase 1; ADI 1; Adi1; ADI1; APL1; ARD; EC 1.13.; Fe ARD; FLJ10913; HMFT1638; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MT1 MMP cytoplasmic tail binding protein 1; MTCBP 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD; SIPL; Submergence induced protein 2; Submergence induced protein 2 homolog; Submergence induced protein like factor; Submergence-induced protein 2 homolog
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