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| Cat.No | ACP14608 | Target Name | PLCD3 |
|---|---|---|---|
| Target Synonyms | 5-bisphosphate phosphodiesterase delta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3, PLCD3; KIAA1964; 1-phosphatidylinositol 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-789 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N3E9 |
|---|
Uniprot Id
Q8N3E9
Target Species
Human
Target Name
PLCD3
Target Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
Target Function
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling.
Target Subcellular Location
Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow.
Target Tissue Specificity
Present in corneal epithelial cells (at protein level).
Target Research Area
Signal Transduction
Target Synonyms
PLCD3; KIAA1964; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3
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