Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

Cat.No	ACP23213	Target Name	PSMD7
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-324	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP23213

Target Name

PSMD7

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-324

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P51665

Background Information

Uniprot Id

P51665
Target Species

Human
Target Name

PSMD7
Target Full Name

26S proteasome non-ATPase regulatory subunit 7
Target Function

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Target Protein Families

Peptidase M67A family
Target Synonyms

26S proteasome non ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; integration site gene; mouse; homolog of; Moloney leukemia virus 34 proviral; Moloney leukemia virus 34 proviral integration; MOV34; Mov34 homolog; Mov34 protein homolog; MOV34L; P40; Proteasome (prosome; macropain) 26S subunit; non ATPase 7; Proteasome (prosome; macropain) 26S subunit; non ATPase; 7 (Mov34 homolog); Proteasome 26S S12; Proteasome 26S subunit; no-ATPase; 7; Proteasome subunit p40; PSD7_HUMAN; PSMD 7; PSMD7; Rpn8; S12
Target Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

Specifications

Immunogen Information

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