Recombinant Human 28S ribosomal protein S28, mitochondrial (MRPS28)

Uniprot Id

Q9Y2Q9

Target Species

Human

Target Name

MRPS28

Target Full Name

Small ribosomal subunit protein bS1m

Target Subcellular Location

Mitochondrion.

Target Protein Families

Bacterial ribosomal protein bS1 family

Target Synonyms

28S ribosomal protein S28; 28S ribosomal protein S35; HSPC007; Mitochondrial 28S ribosomal protein S35; mitochondrial; Mitochondrial ribosomal protein S28; MRP-S28; MRP-S35; MRPS 28; mrps28; MRPS35; RT28_HUMAN; S28mt; S35mt

Target Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature.