Home Products Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 (HSD3B7), Truncated

Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 (HSD3B7), Truncated

ACP07425

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Specifications

Cat.No	ACP07425	Target Name	HSD3B7
Target Synonyms	7-alpha-diol 3-beta-dehydrogenase	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9H2F3

Background Information

Uniprot Id

Q9H2F3
Target Species

Human
Target Name

HSD3B7
Target Full Name

3 beta-hydroxysteroid dehydrogenase type 7
Target Function

The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis. Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Target Involvement

Congenital bile acid synthesis defect 1 (CBAS1)
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

3-beta-HSD family
Target Synonyms

HSD3B7; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5-C27 steroid oxidoreductase; C(27 3-beta-HSD; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase

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Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 (HSD3B7), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 (HSD3B7), Truncated Now

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