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Recombinant Human 39S ribosomal protein L17, mitochondrial (MRPL17)

ACP10273

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10273 Target NameMRPL17
Target SynonymsMRPL17; LIP2; 39S ribosomal protein L17; mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2; Mitochondrial large ribosomal subunit protein bL17mFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range9-175
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NRX2
Background Information
  • Uniprot Id

    Q9NRX2

  • Target Species

    Human

  • Target Name

    MRPL17

  • Target Full Name

    Large ribosomal subunit protein bL17m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Bacterial ribosomal protein bL17 family

  • Target Tissue Specificity

    Detected in adrenal gland, mammary gland and adipose tissue.

  • Target Synonyms

    MRPL17; LIP2; 39S ribosomal protein L17; mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2; Mitochondrial large ribosomal subunit protein bL17m

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

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