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| Cat.No | ACP20570 | Target Name | MRPL33 |
|---|---|---|---|
| Target Synonyms | 39S ribosomal protein L33; L33mt; mitochondrial; MRP-L33; mRpL33; RM33_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-65 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75394 |
|---|
Uniprot Id
O75394
Target Species
Human
Target Name
MRPL33
Target Full Name
Large ribosomal subunit protein bL33m
Target Subcellular Location
Mitochondrion.
Target Protein Families
Bacterial ribosomal protein bL33 family
Target Synonyms
39S ribosomal protein L33; L33mt; mitochondrial; MRP-L33; mRpL33; RM33_HUMAN
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternatively spliced transcript variants encoding different isoforms have been described.
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