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The region for expressing recombinant Human RPS18 contains amino acids 2-152. This RPS18 protein is expected to have a theoretical molecular weight of 44.6 kDa. The RPS18 protein was expressed in e.coli. The N-terminal GST tag was fused into the coding gene segment of RPS18, making it easier to detect and purify the RPS18 recombinant protein in the later stages of expression and purification.The human 40S ribosomal protein S18 (RPS18) is a constituent of the small subunit (40S) of the eukaryotic ribosome. RPS18 plays a fundamental role in protein synthesis. RPS18 contributes to the formation of the ribosomal subunit, aiding in the assembly and stabilization of the small ribosomal particle. The ribosome, composed of both small and large subunits, functions as a molecular machine for translating mRNA into proteins. Research on RPS18 delves into understanding its precise role in ribosomal function, protein synthesis, and its potential implications in cellular processes and diseases associated with aberrations in translation machinery.
The region for expressing recombinant Human RPS18 contains amino acids 2-152. This RPS18 protein is expected to have a theoretical molecular weight of 44.6 kDa. The RPS18 protein was expressed in e.coli. The N-terminal GST tag was fused into the coding gene segment of RPS18, making it easier to detect and purify the RPS18 recombinant protein in the later stages of expression and purification.The human 40S ribosomal protein S18 (RPS18) is a constituent of the small subunit (40S) of the eukaryotic ribosome. RPS18 plays a fundamental role in protein synthesis. RPS18 contributes to the formation of the ribosomal subunit, aiding in the assembly and stabilization of the small ribosomal particle. The ribosome, composed of both small and large subunits, functions as a molecular machine for translating mRNA into proteins. Research on RPS18 delves into understanding its precise role in ribosomal function, protein synthesis, and its potential implications in cellular processes and diseases associated with aberrations in translation machinery.
| Cat.No | ACP03037 | Target Name | RPS18 |
|---|---|---|---|
| Target Synonyms | 40S ribosomal protein S18; HKE3; KE 3; Ke-3; Ke3; Rhabdomyosarcoma antigen MU-RMS-40.21; Ribosomal protein S18; rps18; RS18_HUMAN | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 2-152aa |
| Mol Weight | 44.6kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P62269 |
|---|
Uniprot Id
P62269
Target Species
Human
Target Name
RPS18
Target Full Name
Small ribosomal subunit protein uS13
Target Function
Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Universal ribosomal protein uS13 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
40S ribosomal protein S18; HKE3; KE 3; Ke-3; Ke3; Rhabdomyosarcoma antigen MU-RMS-40.21; Ribosomal protein S18; rps18; RS18_HUMAN
Target Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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