Recombinant Human 40S ribosomal protein S18 (RPS18)

Uniprot Id

P62269

Target Species

Human

Target Name

RPS18

Target Full Name

Small ribosomal subunit protein uS13

Target Function

Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Universal ribosomal protein uS13 family

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

40S ribosomal protein S18; HKE3; KE 3; Ke-3; Ke3; Rhabdomyosarcoma antigen MU-RMS-40.21; Ribosomal protein S18; rps18; RS18_HUMAN

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.