Recombinant Human 40S ribosomal protein S3a (RPS3A)

Uniprot Id

P61247

Target Species

Human

Target Name

RPS3A

Target Full Name

Small ribosomal subunit protein eS1

Target Function

May play a role during erythropoiesis through regulation of transcription factor DDIT3.

Target Subcellular Location

Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Target Protein Families

Eukaryotic ribosomal protein eS1 family

Target Synonyms

40S ribosomal protein S3a; Fte 1; Fte-1; FTE1; MFTL; ribosomal protein S3A; RPS3A; RS3A_HUMAN; S3A; v fos transformation effector protein 1; v fos transformation effector protein; V-fos transformation effector protein

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants have been found for this gene.