Recombinant Human 40S ribosomal protein S8 (RPS8)

Uniprot Id

P62241

Target Species

Human

Target Name

RPS8

Target Full Name

Small ribosomal subunit protein eS8

Target Subcellular Location

Cytoplasm. Membrane; Lipid-anchor. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Target Protein Families

Eukaryotic ribosomal protein eS8 family

Target Synonyms

40S ribosomal protein S8; OK/SW-cl.83; OTTHUMP00000010160; OTTHUMP00000010161; Ribosomal protein S8; RPS8; RS8_HUMAN; S8

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.