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Recombinant Human 43 kDa receptor-associated protein of the synapse (RAPSN)

ACP18497

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18497 Target NameRAPSN
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range2-412Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ13702
Background Information
  • Uniprot Id

    Q13702

  • Target Species

    Human

  • Target Name

    RAPSN

  • Target Full Name

    43 kDa receptor-associated protein of the synapse

  • Target Function

    Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.

  • Target Involvement

    Myasthenic syndrome, congenital, 11, associated with acetylcholine receptor deficiency (CMS11); Fetal akinesia deformation sequence (FADS)

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of postsynaptic membranes.

  • Target Protein Families

    RAPsyn family

  • Target Synonyms

    43 kD receptor associated protein of the synapse; 43 kDa postsynaptic protein; 43 kDa receptor-associated protein of the synapse; Acetylcholine receptor associated 43 kda protein ; Acetylcholine receptor-associated 43 kDa protein; CMS1D; CMS1E; MGC3597; RAPSN; RAPSN_HUMAN; RAPsyn; Receptor associated protein of the synapse 43kD; Receptor associated protein of the synapse; RING finger protein 205; RNF 205; RNF205

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