Home Products Recombinant Human 5′-3′ exonuclease PLD4 (PLD4), Truncated

Recombinant Human 5′-3′ exonuclease PLD4 (PLD4), Truncated

ACP03942

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Specifications

Cat.No	ACP03942	Target Name	PLD4
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	52-506aa	Mol Weight	66.0kDa
Protein Length	Partial	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96BZ4

Background Information

Uniprot Id

Q96BZ4
Target Species

Human
Target Name

PLD4
Target Full Name

5'-3' exonuclease PLD4
Target Function

5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Nucleus. Early endosome. Cytoplasmic vesicle, phagosome.
Target Protein Families

Phospholipase D family
Target Research Area

Cardiovascular
Target Synonyms

C14orf175; Choline phosphatase 4; EC 3.1.4.4; Phosphatidylcholine hydrolyzing phospholipase D4; Phosphatidylcholine-hydrolyzing phospholipase D4; Phospholipase D family member 4; Phospholipase D4; PLD 4; PLD4; PLD4_HUMAN
Target Background

Predicted to enable single-stranded DNA 5'-3' exodeoxyribonuclease activity. Predicted to be involved in hematopoietic progenitor cell differentiation; phagocytosis; and regulation of cytokine production involved in inflammatory response. Predicted to be located in early endosome and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including endoplasmic reticulum; phagocytic vesicle; and trans-Golgi network membrane.

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Recombinant Human 5′-3′ exonuclease PLD4 (PLD4), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human 5′-3′ exonuclease PLD4 (PLD4), Truncated Now

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