Recombinant Human 60S ribosomal protein L28 (RPL28)

Uniprot Id

P46779

Target Species

Human

Target Name

RPL28

Target Full Name

Large ribosomal subunit protein eL28

Target Function

Component of the large ribosomal subunit.

Target Protein Families

Eukaryotic ribosomal protein eL28 family

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

60S ribosomal protein L28; FLJ 43307 ; FLJ43307 ; L 28; L28; Ribosomal protein L28 ; RL28_HUMAN; RPL 28 ; rpl28

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.