Recombinant Human 60S ribosomal protein L34 (RPL34)

Uniprot Id

P49207

Target Species

Human

Target Name

RPL34

Target Full Name

Large ribosomal subunit protein eL34

Target Function

Component of the large ribosomal subunit.

Target Subcellular Location

Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum.

Target Protein Families

Eukaryotic ribosomal protein eL34 family

Target Synonyms

60S ribosomal protein L34; L34; MGC111005; Ribosomal protein L34; RL34_HUMAN; rpl34

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Overexpression of this gene has been observed in some cancer cells. Alternative splicing results in multiple transcript variants, all encoding the same isoform. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.