Recombinant Human 60S ribosomal protein L8 (RPL8)

Uniprot Id

P62917

Target Species

Human

Target Name

RPL8

Target Full Name

Large ribosomal subunit protein uL2

Target Function

Component of the large ribosomal subunit.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Universal ribosomal protein uL2 family

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

60S ribosomal protein L8; L8; Ribosomal protein L8; RL8_HUMAN; RPL 8; rpl8

Target Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.