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| Cat.No | ACP12012 | Target Name | ABHD10 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 53-306 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NUJ1 |
|---|
Uniprot Id
Q9NUJ1
Target Species
Human
Target Name
ABHD10
Target Full Name
Palmitoyl-protein thioesterase ABHD10, mitochondrial
Target Function
Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate.
Target Subcellular Location
Mitochondrion.
Target Protein Families
AB hydrolase superfamily
Target Synonyms
Abhd10; ABHDA_HUMAN; Abhydrolase domain containing 10; Abhydrolase domain-containing protein 10; Abhydrolase domain-containing protein 10; mitochondrial; Alpha/beta hydrolase domain containing protein 10 mitochondrial; mitochondrial; Mycophenolic acid acyl glucuronide esterase mitochondrial
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