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Recombinant Human Acetolactate synthase-like protein (ILVBL), Truncated

ACP06844

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06844 Target NameILVBL
Target SynonymsILVBL; AHAS; HACL2; 2-hydroxyacyl-CoA lyase 2; Acetolactate synthase-like protein; IlvB-like proteinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDA1L0T0
Background Information
  • Uniprot Id

    A1L0T0

  • Target Species

    Human

  • Target Name

    ILVBL

  • Target Full Name

    2-hydroxyacyl-CoA lyase 2

  • Target Function

    Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the phytosphingosine degradation pathway.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    TPP enzyme family

  • Target Tissue Specificity

    Expressed in all tissues tested, with highest expression in heart, pancreas and placenta.

  • Target Synonyms

    ILVBL; AHAS; HACL2; 2-hydroxyacyl-CoA lyase 2; Acetolactate synthase-like protein; IlvB-like protein

  • Target Background

    The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The highest degree of similarity is found with bacterial acetolactate synthases (AHAS), which are enzymes that catalyze the first step in branched-chain amino acid biosynthesis.

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