Recombinant Human Acetyl-CoA acetyltransferase, cytosolic (ACAT2)

Uniprot Id

Q9BWD1

Target Species

Human

Target Name

ACAT2

Target Full Name

Acetyl-CoA acetyltransferase, cytosolic

Target Function

Involved in the biosynthetic pathway of cholesterol.

Target Subcellular Location

Cytoplasm, cytosol.

Target Protein Families

Thiolase family

Target Research Area

Metabolism

Target Synonyms

Acat2; acetoacetyl CoA thiolase; acetoacetyl Coenzyme A thiolase; Acetyl CoA acetyltransferase; Acetyl CoA transferase like protein ; acetyl Coenzyme A acetyltransferase 2 ; Acetyl-CoA acetyltransferase; Acetyl-CoA transferase-like protein; Acyl Coenzyme A cholesterol acyltransferase 2; Cytosolic acetoacetyl-CoA thiolase; cytosolic; SOAT2; THIC_HUMAN

Target Background

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.