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| Cat.No | ACP14467 | Target Name | SMPDL3B |
|---|---|---|---|
| Target Synonyms | SMPDL3B; ASML3B; ASMLPDAcid sphingomyelinase-like phosphodiesterase 3b; ASM-like phosphodiesterase 3b; EC 3.1.4.- | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 19-455 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92485 |
|---|
Uniprot Id
Q92485
Target Species
Human
Target Name
SMPDL3B
Target Full Name
Acid sphingomyelinase-like phosphodiesterase 3b
Target Function
Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro).
Target Subcellular Location
Secreted. Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Acid sphingomyelinase family
Target Synonyms
SMPDL3B; ASML3B; ASMLPDAcid sphingomyelinase-like phosphodiesterase 3b; ASM-like phosphodiesterase 3b; EC 3.1.4.-
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