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| Cat.No | ACP00406 | Target Name | ACTB |
|---|---|---|---|
| Target Synonyms | Beta-actin | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Expression Range | 1-375aa |
| Mol Weight | 42.6 kDa | Protein Length | Full length |
| Purity | Greater than 95% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P60709 |
|---|
Uniprot Id
P60709
Target Species
Human
Target Name
ACTB
Target Full Name
Actin, cytoplasmic 1
Target Function
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
Target Involvement
Dystonia, juvenile-onset (DJO); Baraitser-Winter syndrome 1 (BRWS1)
Target Subcellular Location
Cytoplasm, cytoskeleton. Nucleus.
Target Protein Families
Actin family
Target Research Area
Signal Transduction
Target Synonyms
A26C1A; A26C1B; ACTB; ACTB_HUMAN; Actin beta; Actin cytoplasmic 1; Actin; cytoplasmic 1; N-terminally processed; Actx; b actin; b-actin; Beta cytoskeletal actin; Beta-actin; BRWS1; E430023M04Rik; Melanoma X actin; MGC128179; PS1TP5 binding protein 1; PS1TP5BP1
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