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| Cat.No | ACP01943 | Target Name | ATF7IP2 |
|---|---|---|---|
| Target Synonyms | ATF7-interacting protein 2;MBD1-containing chromatin-associated factor 2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Mol Weight | 81.7 kDa |
| Protein Length | Full length | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5U623 |
|---|
Uniprot Id
Q5U623
Target Species
Human
Target Name
ATF7IP2
Target Full Name
Activating transcription factor 7-interacting protein 2
Target Function
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable).
Target Subcellular Location
Nucleus.
Target Protein Families
MCAF family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
ATF7IP2; MCAF2Activating transcription factor 7-interacting protein 2; ATF7-interacting protein 2; MBD1-containing chromatin-associated factor 2
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