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| Cat.No | ACP01493 | Target Name | AK7 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Yeast |
| Expression Range | 1-723aa | Mol Weight | 83.7 kDa |
| Protein Length | Full length | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96M32 |
|---|
Uniprot Id
Q96M32
Target Species
Human
Target Name
AK7
Target Full Name
Adenylate kinase 7
Target Function
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.
Target Subcellular Location
Cytoplasm, cytosol. Cell projection, cilium, flagellum.
Target Protein Families
Adenylate kinase family; Dpy-30 family
Target Tissue Specificity
Expressed in sperm and airway epithelial cells (at protein level).
Target Research Area
Metabolism
Target Synonyms
AK7; Adenylate kinase 7; AK 7; EC 2.7.4.3; EC 2.7.4.6; ATP-AMP transphosphorylase 7
Target Background
This gene encodes a member of the adenylate kinase family of enzymes. The encoded enzyme is a phosphotransferase that catalyzes the reversible phosphorylation of adenine nucleotides. This enzyme plays a role in energy homeostasis of the cell. Alternative splicing results in multiple transcript variants. Mutations in the mouse gene are associated with primary ciliary dyskinesia.
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