Recombinant Human ADP-ribosylation factor-like protein 4D (ARL4D)

Uniprot Id

P49703

Target Species

Human

Target Name

ARL4D

Target Full Name

ADP-ribosylation factor-like protein 4D

Target Function

Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.

Target Subcellular Location

Nucleus, nucleolus. Cell membrane. Nucleus. Cytoplasm.

Target Protein Families

Small GTPase superfamily, Arf family

Target Research Area

Signal Transduction

Target Synonyms

ADP ribosylation factor 4 like; ADP ribosylation factor like 4D; ADP ribosylation factor like 6; ADP ribosylation factor like protein 4D; ADP ribosylation factor like protein 4L; ADP-ribosylation factor-like protein 4D; ADP-ribosylation factor-like protein 4L; AR L6; ARF 4L; ARF4L; ARL 4D; ARL 6; ARL4D; ARL4D_HUMAN; ARL6

Target Background

ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking.