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| Cat.No | ACP17287 | Target Name | AKIRIN2 |
|---|---|---|---|
| Target Synonyms | AKIR2_HUMAN; AKIRIN 2; Akirin-2; Akirin2; C6orf166; dJ486L4.2; FBI1; FLJ10342; Fourteen three three beta interactant 1; OTTHUMP00000016836 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-203 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q53H80 |
|---|
Uniprot Id
Q53H80
Target Species
Human
Target Name
AKIRIN2
Target Full Name
Akirin-2
Target Function
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
Target Subcellular Location
Nucleus.
Target Protein Families
Akirin family
Target Tissue Specificity
Widely expressed with the highest expression in peripheral blood leukocytes.
Target Synonyms
AKIR2_HUMAN; AKIRIN 2; Akirin-2; Akirin2; C6orf166; dJ486L4.2; FBI1; FLJ10342; Fourteen three three beta interactant 1; OTTHUMP00000016836
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