Home Products Recombinant Human All-trans-retinol 13,14-reductase (RETSAT)

Recombinant Human All-trans-retinol 13,14-reductase (RETSAT)

ACP15910

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Specifications

Cat.No	ACP15910	Target Name	RETSAT
Target Synonyms	14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene protein, 14-reductase; EC 1.3.99.23; All-trans-13, RETSAT; PPSIG; UNQ439/PRO872; All-trans-retinol 13	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	19-610
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6NUM9

Background Information

Uniprot Id

Q6NUM9
Target Species

Human
Target Name

RETSAT
Target Full Name

All-trans-retinol 13,14-reductase
Target Function

Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation.
Target Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Protein Families

Carotenoid/retinoid oxidoreductase family, CrtISO subfamily
Target Tissue Specificity

Expressed in liver; expression positively correlates with obesity and liver steatosis. Expressed in adipose tissue; expression tends to be decreased in obese versus lean individuals.
Target Synonyms

RETSAT; PPSIG; UNQ439/PRO872; All-trans-retinol 13,14-reductase; EC 1.3.99.23; All-trans-13,14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene protein

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Recombinant Human All-trans-retinol 13,14-reductase (RETSAT)

Specifications

Immunogen Information

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