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| Cat.No | ACP19971 | Target Name | MGAT4D |
|---|---|---|---|
| Target Synonyms | 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; N-acetylglucosaminyltransferase MGAT1 inhibitory protein; GlcNAcT-I inhibitory protein; GnT1IP, MGAT4DAlpha-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 25-374 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A6NG13 |
|---|
Uniprot Id
A6NG13
Target Species
Human
Target Name
MGAT4D
Target Full Name
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Target Function
May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 54 family
Target Tissue Specificity
Expressed in testis. Poorly expressed in testis biopsies from men with impaired spermatogenesis.
Target Synonyms
MGAT4DAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; N-acetylglucosaminyltransferase MGAT1 inhibitory protein; GlcNAcT-I inhibitory protein; GnT1IP
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