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| Cat.No | ACP24036 | Target Name | NAGA |
|---|---|---|---|
| Target Synonyms | NAGA; Alpha-N-acetylgalactosaminidase; EC 3.2.1.49; Alpha-galactosidase B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 18-411 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P17050 |
|---|
Uniprot Id
P17050
Target Species
Human
Target Name
NAGA
Target Full Name
Alpha-N-acetylgalactosaminidase
Target Function
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.
Target Involvement
Schindler disease (SCHIND); Kanzaki disease (KANZD)
Target Subcellular Location
Lysosome.
Target Protein Families
Glycosyl hydrolase 27 family
Target Synonyms
NAGA; Alpha-N-acetylgalactosaminidase; EC 3.2.1.49; Alpha-galactosidase B
Target Background
NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).
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